Arizona Cardinals open as big underdogs for week one of the 2024 season against Buffalo Bills

The Arizona Cardinals open as seven-point underdogs ahead of the 2024 NFL season.

The Arizona Cardinals won only four games last season and have the blessing of opening up their 2024 schedule with a cross country trip against the Buffalo Bills.

That is how week one of the 2024 NFL season will kickoff, and for the Arizona Cardinals they are the second biggest underdogs of the opening weekend so far according to our friends at DraftKings Sportsbook.

The Arizona Cardinals open as seven-point underdogs against the Bills for week one.

Only the New England Patriots open up as bigger dogs, as they are eight-point road dogs to the Cincinnati Bengals.

That is a massive number to open up as a dog four months before the season, so we will see how this changes over the course of the offseason, training camp and preseason.

The Bills have had quite the overhaul, but they have Josh Allen, which makes them favorites for a lot of games heading into the season.

Check out DraftKings Sportsbook, the official sportsbook partner of SB Nation.