Colts vs. Browns: Prediction, point spread, best bet in Week 7

The Indianapolis Colts (3-3) play the Cleveland Browns (3-2) on Sunday, and if you’re looking to do some last-minute betting research, you’re in luck! We’ll give you the latest point spread, money line odds and over/under number, as well as the information you’ll need to make the smartest bet.

The game starts at 1:00 p.m. ET and can be seen on CBS.

In a meeting for the first time since the 2020 season, the Browns have been scratching their way to some wins this season despite a shoulder injury to starting quarterback Deshaun Watson and a season-ending knee injury that Nick Chubb suffered in Week 2. The Colts showed plenty of promise early on during the campaign but without rookie Anthony Richardson, the offense hasn’t had the same level of ceiling and upside.

• Point spread: Colts +3.5
• Money line: +145 Colts / -175 Browns
• Over-under: 40.5

Colts vs. Browns injury report:

Colts RT Braden Smith (wrist/hip) and TE Kylen Granson (concussion) were ruled out on the final injury report while WR Alec Pierce (shoulder) is listed as questionable.

The Browns ruled out only LB Sione Takitaki (hamstring) while labeling TE Harrison Bryant (hip), RB Kareem Hunt (thigh), CB Greg Newsome (hamstring) and QB Deshaun Watson (shoulder) as questionable on their final injury report.

Check out the latest injury report here.

Advice and prediction

Total points UNDER 40.5

There’s a good chance both teams will be without their starting quarterbacks. Rookie Anthony Richardson is scheduled to undergo season-ending shoulder surgery while Deshaun Watson has missed the last two games due to his own shoulder injury. This matchup is going to feature defense and rushing attacks. The Colts struggled offensively until the fourth quarter in Week 6, scoring just six points before adding two touchdowns in garbage time. The Browns have scored just one touchdown and 22 total points in the last two games without Watson under center. Even if Watson returns for the first time since Sept. 24, this game is shaping up to be a low-scoring affair.

Prediction: Browns 20, Colts 17

Get more betting analysis and predictions at Sportsbook Wire.