2021 NFL Week 1: Lions vs 49ers Game Highlights 1 min read 3 years ago By: Detroit Lions Watch More at Detroit Lions Share this:TwitterFacebookLinkedInPinterestRedditTumblrWhatsAppPocketPrintLike this:Like Loading... Related Tags: 2021 49ers detroit Detroit Lions game’ highlights lions NFC NFL Video. YouTube Videos week YouTube Continue Reading Previous T.J. Watt breaks down his, and the Steelers’ defense, dominant performance vs. the BillsNext Sam Darnold speaks about playing the Jets in the opener